Yun‐Chi Lu

Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo

Kai-Wen Cheng, Chih-Hua Tseng, Cherng‐Chyi Tzeng et al. · Pharmacological Research · 2018 · 87 citations

Health Sciences, Microbial Pathogens, Gastrointestinal Pharmacology +9

SN38-loaded <100 nm targeted liposomes for improving poor solubility and minimizing burst release and toxicity: in vitro and in vivo study

Yi‐Ping Fang, Chih-Hung Chuang, Yi‐Jhun Wu et al. · International Journal of Nanomedicine · 2018 · 44 citations · Full text

Selective antibody activation through protease-activated pro-antibodies that mask binding sites with inhibitory domains

I‐Ju Chen, Chih-Hung Chuang, Yuan-Chin Hsieh et al. · Scientific Reports · 2017 · 43 citations · Full text

Specific Inhibition of Bacterial β-Glucuronidase by Pyrazolo[4,3-<i>c</i>]quinoline Derivatives via a pH-Dependent Manner To Suppress Chemotherapy-Induced Intestinal Toxicity

Kai-Wen Cheng, Chih-Hua Tseng, Chia‐Ning Yang et al. · Journal of Medicinal Chemistry · 2017 · 39 citations

Enhanced drug internalization and therapeutic efficacy of PEGylated nanoparticles by one-step formulation with anti-mPEG bispecific antibody in intrinsic drug-resistant breast cancer

Yi‐An Cheng, I‐Ju Chen, Yu-Cheng Su et al. · Biomaterials Science · 2019 · 36 citations · Full text