Matthias Zentgraf

A Small Nonrule of 3 Compatible Fragment Library Provides High Hit Rate of Endothiapepsin Crystal Structures with Various Fragment Chemotypes

Helene Köster, Tobias Craan, Sascha Brass et al. · Journal of Medicinal Chemistry · 2011 · 117 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions

H. Steuber, Matthias Zentgraf, Christof Gerlach et al. · Journal of Molecular Biology · 2006 · 109 citations

Pharmacy, Biochemistry, Medicinal Chemistry +9

Mining Electronic Laboratory Notebooks: Analysis, Retrosynthesis, and Reaction Based Enumeration

Clara D. Christ, Matthias Zentgraf, Jan M. Kriegl · Journal of Chemical Information and Modeling · 2012 · 104 citations

Natural Sciences, Bioinformatics, Chemistry +17

How Reliable Are Current Docking Approaches for Structure‐Based Drug Design? Lessons from Aldose Reductase

Matthias Zentgraf, H. Steuber, C. Koch et al. · Angewandte Chemie International Edition · 2007 · 62 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17

High-resolution Crystal Structure of Aldose Reductase Complexed with the Novel Sulfonyl-pyridazinone Inhibitor Exhibiting an Alternative Active Site Anchoring Group

H. Steuber, Matthias Zentgraf, A. Podjarny et al. · Journal of Molecular Biology · 2005 · 53 citations

Life Sciences, Biochemistry, Medicinal Chemistry +11