Sharan R. Srinivasan

Analogues of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, As Anti-Cancer Agents

Xiaokai Li, Sharan R. Srinivasan, Jamie N. Connarn et al. · ACS Medicinal Chemistry Letters · 2013 · 160 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels

Yoshinari Miyata, Xiaokai Li, Hsiu-Fang Lee et al. · ACS Chemical Neuroscience · 2013 · 133 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Cysteine Reactivity Distinguishes Redox Sensing by the Heat-Inducible and Constitutive Forms of Heat Shock Protein 70

Yoshinari Miyata, Jennifer N. Rauch, Umesh K. Jinwal et al. · Chemistry & Biology · 2012 · 94 citations

Life Sciences, Biochemistry, Molecular Biology +16

Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy

Zapporah T. Young, Jennifer N. Rauch, Victoria A. Assimon et al. · Cell chemical biology · 2016 · 89 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades

Sharan R. Srinivasan, Laura C. Cesa, Xiaokai Li et al. · Molecular Cancer Research · 2017 · 53 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17