Zapporah T. Young - Concepedia

Author

Zapporah T. Young

University of California, San Francisco ORCID

Also Known As

Juan Zhang, Z.T. Young, Zapporah T. Young, Zapporah Young, Zapporah T. Young

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

University of California, San Francisco University of Michigan University of Pittsburgh University of South Florida University of Pavia

About

Zapporah T. Young is an author at University of California, San Francisco specializing in medicine, molecular biology, and systems biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	524
2	Molecular Biology	4	4	340
3	Natural Sciences	2	2	152
4	Biochemistry	2	2	152
5	Cell Biology	2	2	267

Zapporah T. Young

Publications

Citations

H-Index

Page 1

	Year	Citations
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice Benjamı́n Caballero, Mathieu Bourdenx, Enrique Luengo, Nature Communications	2021	201
Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks Teresa A. Colvin, Vladimir L. Gabai, Jianlin Gong, Cancer Research Cancer ResearchProtein Quality ControlTranscriptional RegulationSignaling PathwayCell Regulation	2014	184
Analogues of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, As Anti-Cancer Agents Xiaokai Li, Sharan R. Srinivasan, Jamie N. Connarn, ACS Medicinal Chemistry Letters	2013	154
Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels Yoshinari Miyata, Xiaokai Li, Hsiu-Fang Lee, ACS Chemical Neuroscience Hsp70 InhibitorsMolecular BiologyNeurochemical BiomarkersPre-clinical PharmacologyMolecular Pharmacology	2013	127
Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein–Protein Interactions with Heat Shock Protein 70 (Hsp70) Hao Shao, Xiaokai Li, Michael A. Moses, Journal of Medicinal Chemistry	2018	115
Allosteric Heat Shock Protein 70 Inhibitors Rapidly Rescue Synaptic Plasticity Deficits by Reducing Aberrant Tau Jose F. Abisambra, Umesh K. Jinwal, Yoshinari Miyata, Biological Psychiatry Synaptic PlasticityProtein FunctionMolecular NeuroscienceSignal TransductionAberrant Tau	2013	105
Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy Zapporah T. Young, Jennifer N. Rauch, Victoria A. Assimon, Cell chemical biology Protein FunctionSignal TransductionProtein FoldingMolecular BiologyDegenerative Pathology	2016	83
A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein–Protein Interactions Silvia Rinaldi, Victoria A. Assimon, Zapporah T. Young, ACS Chemical Biology Protein AssemblyMolecular BiologyAllosteric InhibitorsAnalytical UltracentrifugationProtein Folding	2018	25
Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells Isabelle R. Taylor, Victoria A. Assimon, Szu Yu Kuo, Chemical Science	2020	21
A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities Hao Shao, Shuhei Taguwa, Luke A. Gilbert, Cell chemical biology	2022	12

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