Nicole A. Housley

Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function

Jonathon P. Audia, Xi‐Ming Yang, Edward S. Crockett et al. · Basic Research in Cardiology · 2018 · 174 citations · Full text

Long-term Reduction, Heart Failure, Cardiovascular Disease +10

The Highly Selective Caspase-1 Inhibitor VX-765 Provides Additive Protection Against Myocardial Infarction in Rat Hearts When Combined With a Platelet Inhibitor

Xi‐Ming Yang, James M. Downey, Michael V. Cohen et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 2017 · 53 citations · Full text

The Rickettsia prowazekii ExoU Homologue Possesses Phospholipase A ₁ (PLA ₁ ), PLA ₂ , and Lyso-PLA ₂ Activities and Can Function in the Absence of Any Eukaryotic Cofactors <i>In Vitro</i>

Nicole A. Housley, Herbert H. Winkler, Jonathon P. Audia · Journal of Bacteriology · 2011 · 35 citations · Full text

Bioorganic Chemistry, Active Rp534, Molecular Biology +18

Virulent <i>Pseudomonas aeruginosa</i> infection converts antimicrobial amyloids into cytotoxic prions

S.B. Voth, M.S. Gwin, C. Michael Francis et al. · The FASEB Journal · 2020 · 35 citations · Full text

Protein Secretion, Pathogenic Microbiology, Immunology +17

In the Absence of Effector Proteins, the Pseudomonas aeruginosa Type Three Secretion System Needle Tip Complex Contributes to Lung Injury and Systemic Inflammatory Responses

Jonathon P. Audia, Ashley S. Lindsey, Nicole A. Housley et al. · PLoS ONE · 2013 · 27 citations · Full text

Acute Lung Injury, Inflammatory Lung Disease, Microbial Pathogens +23