Concepedia

Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function

Jonathon P. Audia, Xi‐Ming Yang, Edward S. Crockett, Nicole A. Housley, Ehtesham Ul Haq, Kristen O’Donnell, Michael V. Cohen, James M. Downey, Diego F. Alvarez

Basic Research in Cardiology · 2018 · 178 citations · 30 references

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References

30

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations

, , +14

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee et al. · Nature · 2015 · 3.7K citations

, , +13

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

Edward T. Chouchani, Victoria R. Pell, Edoardo Gaude et al. · Nature · 2014 · 2.8K citations

, , +16

High-Resolution Respirometry: OXPHOS Protocols for Human Cells and Permeabilized Fibers from Small Biopsies of Human Muscle

Dominik Pesta, Erich Gnaiger · Methods in molecular biology · 2011 · 996 citations

, , +8