James P. Madigan

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

Brian C. Capell, Michael R. Erdos, James P. Madigan et al. · Proceedings of the National Academy of Sciences · 2005 · 388 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +4

Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes

Matthew D. Hall, Katherine A. Telma, Ki-Eun Chang et al. · Cancer Research · 2014 · 374 citations

Medicine, Oncology, Pharmacology +9

Rho Family GTPase Modification and Dependence on CAAX Motif-signaled Posttranslational Modification

Patrick J. Roberts, Natalia Mitin, Patricia J. Keller et al. · Journal of Biological Chemistry · 2008 · 361 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis

James P. Madigan · Nucleic Acids Research · 2002 · 293 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity

Lothar Esser, Fei Zhou, Kristen M. Pluchino et al. · Journal of Biological Chemistry · 2016 · 181 citations · Full text

Life Sciences, Molecular Biology, Pharmacokinetics +13