Brian C. Capell

Cytoplasmic chromatin triggers inflammation in senescence and cancer

Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli et al. · Nature · 2017 · 1.2K citations · Full text

Chromatin, Chromatin Remodeling, Medicine +5

Autophagy mediates degradation of nuclear lamina

Zhixun Dou, Caiyue Xu, Greg Donahue et al. · Nature · 2015 · 650 citations · Full text

Cell Autophagy, Nuclear Lamina, Autophagy +4

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

Parisha P. Shah, Greg Donahue, Gabriel Otte et al. · Genes & Development · 2013 · 544 citations · Full text

Histone Modifications, Epigenetic Change, Epigenetics +21

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

Brian C. Capell, Michael R. Erdos, James P. Madigan et al. · Proceedings of the National Academy of Sciences · 2005 · 381 citations · Full text

Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson–Gilford progeria syndrome

Renée Varga, Maria Eriksson, Michael R. Erdos et al. · Proceedings of the National Academy of Sciences · 2006 · 291 citations · Full text