John Luff

Senataxin Plays an Essential Role with DNA Damage Response Proteins in Meiotic Recombination and Gene Silencing

Olivier J. Bécherel, Abrey J. Yeo, Alissa Stellati et al. · PLoS Genetics · 2013 · 163 citations · Full text

Cytogenetics, Genetics, Setx Gene +27

Oxidative Stress Is Responsible for Deficient Survival and Dendritogenesis in Purkinje Neurons from Ataxia-Telangiectasia Mutated Mutant Mice

Philip Chen, Cheng Peng, John Luff et al. · Journal of Neuroscience · 2003 · 135 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Purkinje Neurons +13

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype

Hazel Quek, John Luff, KaGeen Cheung et al. · Human Molecular Genetics · 2016 · 86 citations · Full text

Atm Gene, Neurodegenerative Diseases, Neuroanatomy +13

Dramatic extension of tumor latency and correction of neurobehavioral phenotype in Atm-mutant mice with a nitroxide antioxidant

Nuri Gueven, John Luff, Cheng Peng et al. · Free Radical Biology and Medicine · 2006 · 66 citations

Neuro-oncology, Nitrosative Stress, Tumor Latency +10

R-Loops in Proliferating Cells but Not in the Brain: Implications for AOA2 and Other Autosomal Recessive Ataxias

Abrey J. Yeo, Olivier J. Bécherel, John Luff et al. · PLoS ONE · 2014 · 61 citations · Full text

Genetics, Setx Gene, Cell Death +19