Hane Lee

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Ramin Nazarian, Hubing Shi, Qi Wang et al. · Nature · 2010 · 2.1K citations

N-ras Upregulation, Medicine, Melanoma +7

Clinical Exome Sequencing for Genetic Identification of Rare Mendelian Disorders

Hane Lee, Joshua L. Deignan, Naghmeh Dorrani et al. · JAMA · 2014 · 969 citations · Full text

Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance

Hubing Shi, Gatien Moriceau, Xiangju Kong et al. · Nature Communications · 2012 · 615 citations · Full text

Tumor Biology, Radiation Oncology, Engineering +10

Cold Urticaria, Immunodeficiency, and Autoimmunity Related to <i>PLCG2</i> Deletions

Michael J. Ombrello, Elaine F. Remmers, Guangping Sun et al. · New England Journal of Medicine · 2012 · 410 citations · Full text

Exome sequencing-based copy-number variation and loss of heterozygosity detection: ExomeCNV

J. Fah Sathirapongsasuti, Hane Lee, Basil A. Horst et al. · Bioinformatics · 2011 · 386 citations · Full text