Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1

Hijai R. Shin, Y. Rose Citron, Lei Wang, +17

Science

Proteinlipid InteractionMolecular PhysiologySignal TransductionBiochemistryOxysterol +12

The effect of one-lung ventilation upon pulmonary inflammatory responses during lung resection

Yusuke Sugasawa, Keisuke Yamaguchi, Seiichiro Kumakura, +5

Journal of Anesthesia

InflammationOne-lung VentilationLung ResectionInflammatory Lung DiseasePulmonary Inflammatory Responses +9

Site-specific effects of neurosteroids on GABAA receptor activation and desensitization

Yusuke Sugasawa, Wayland W.L. Cheng, John Bracamontes, +10

eLife

Effects of sevoflurane and propofol on pulmonary inflammatory responses during lung resection

Yusuke Sugasawa, Keisuke Yamaguchi, Seiichiro Kumakura, +4

Journal of Anesthesia

InflammationLung ResectionInflammatory Lung DiseasePulmonary Inflammatory ResponsesLung Inflammation +7

Prevalence of chronic postsurgical pain after thoracotomy and total knee arthroplasty: a retrospective multicenter study in Japan (Japanese Study Group of Subacute Postoperative Pain)

Yoko Sugiyama, Hiroki Iida, Fumimasa Amaya, +16

Journal of Anesthesia

Health SciencesPain MedicinePostoperative Pain ManagementChronic Musculoskeletal ConditionPerioperative Pain +9

Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling

Wayland W.L. Cheng, Melissa M. Budelier, Yusuke Sugasawa, +10

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Proteinlipid InteractionMolecular PhysiologyMolecular NeuroscienceBiochemistrySignal Transduction +12

Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel

Melissa M. Budelier, Wayland W.L. Cheng, Zi-Wei Chen, +6

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Proteinlipid InteractionMolecular PhysiologyBiochemistryFunctional SelectivityMedicine +6

Intrasubunit and Intersubunit Steroid Binding Sites Independently and Additively Mediate α1β2γ2L GABAA Receptor Potentiation by the Endogenous Neurosteroid Allopregnanolone

Allison L. Germann, Spencer R. Pierce, Hiroki Tateiwa, +5

Molecular Pharmacology

The molecular determinants of neurosteroid binding in the GABA(A) receptor

Yusuke Sugasawa, John Bracamontes, Kathiresan Krishnan, +7

The Journal of Steroid Biochemistry and Molecular Biology

Molecular NeuroscienceMolecular PhysiologyNeuroanatomyMedicineNeurotransmitter +10

Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol

Seiichiro Kumakura, Keisuke Yamaguchi, Yusuke Sugasawa, +4

Molecular Medicine Reports