Valerio Castoldi

dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice

Gaia Colasante, Gabriele Lignani, Simone Brusco et al. · Molecular Therapy · 2019 · 215 citations · Full text

Dravet Syndrome Mice, Molecular Neuroscience, Experimental Neuropathology +7

Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery

Serena Giannelli, Mirko Luoni, Valerio Castoldi et al. · Human Molecular Genetics · 2017 · 128 citations · Full text

Ocular Disease, Immunology, Molecular Biology +19

AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy

Giuseppe Morabito, Serena Giannelli, Gabriele Ordazzo et al. · Molecular Therapy · 2017 · 126 citations · Full text

Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of Tuberous Sclerosis Complex

Marco Cambiaghi, Marco Cursi, Laura Magri et al. · Neuropharmacology · 2012 · 45 citations

Tuberous Sclerosis Complex, Neurobiology Of Disease, Behavioral Neuroscience +11

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks

Roberta Pennucci, Francesca Talpo, Veronica Astro et al. · Cerebral Cortex · 2015 · 32 citations · Full text

Neurotransmitter, Neurotransmission, Functional Gabaergic Networks +23