Charles T. Jakubik

PTEN Loss Mediates Clinical Cross-Resistance to CDK4/6 and PI3Kα Inhibitors in Breast Cancer

Carlotta Costa, Ye Wang, Amy Ly et al. · Cancer Discovery · 2019 · 245 citations · Full text

Measurement of PIP3 Levels Reveals an Unexpected Role for p110β in Early Adaptive Responses to p110α-Specific Inhibitors in Luminal Breast Cancer

Carlotta Costa, Hiromichi Ebi, Miriam Martini et al. · Cancer Cell · 2014 · 214 citations · Full text

Breast Oncology, Oncology, Medicine +10

Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination

Jungoh Ham, Carlotta Costa, Renata Sano et al. · Cancer Cell · 2016 · 130 citations · Full text

Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer

Anthony C. Faber, Anna F. Farago, Carlotta Costa et al. · Proceedings of the National Academy of Sciences · 2015 · 127 citations · Full text

PI3Kβ is selectively required for growth factor-stimulated macropinocytosis

Gilbert Salloum, Charles T. Jakubik, Zahra Erami et al. · Journal of Cell Science · 2019 · 29 citations · Full text