Carmen Chan

PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D

Eneda Toska, Hatice U. Osmanbeyoglu, Pau Castel et al. · Science · 2017 · 269 citations · Full text

Medicine, Molecular Biology, Oncology +15

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer

Guotai Xu, Sagar Chhangawala, Emiliano Cocco et al. · Nature Genetics · 2020 · 240 citations · Full text

Medicine, Genetics, Oncology +16

Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2)

Emiliano Cocco, F. Javier Carmona, Pedram Razavi et al. · Science Signaling · 2018 · 73 citations · Full text

Medicine, Oncology, Pharmacology +17

PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression

Eneda Toska, Pau Castel, Sagar Chhangawala et al. · Cell Reports · 2019 · 70 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs

Hatice U. Osmanbeyoglu, Eneda Toska, Carmen Chan et al. · Nature Communications · 2017 · 41 citations · Full text

Life Sciences, Cancer Biology, Oncology +17