Christine Dureuil

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

Baptiste Ronan, Odile Flamand, Lionel Vescovi et al. · Nature Chemical Biology · 2014 · 476 citations

Cell Autophagy, Signal Transduction, Cell Trafficking +10

p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53

Christine Wasylyk, Roberto Salvi, Manuela Argentini et al. · Oncogene · 1999 · 113 citations

Medicine, Apoptosis, Cell Death +7

Discovery of (2<i>S</i>)-8-[(3<i>R</i>)-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2<i>H</i>-pyrimido[1,2-<i>a</i>]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Benoit Pasquier, Youssef El‐Ahmad, Bruno Filoche-Rommé et al. · Journal of Medicinal Chemistry · 2014 · 90 citations

Drug Target, Solid Tumors, Exquisite Selectivity +22

Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments

Claude Caron de Fromentel, Nadège Gruel, Corinne Venot et al. · Oncogene · 1999 · 86 citations

Tumor Biology, Tumor Suppressor, Transcriptional Activity +8

CD137 (4-1BB) Engagement Fine-Tunes Synergistic IL-15– and IL-21–Driven NK Cell Proliferation

Laurent Vidard, Christine Dureuil, Jérémy Baudhuin et al. · The Journal of Immunology · 2019 · 75 citations · Full text