Concepedia

William Sinko

WS

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Publications

13

Citations

1.1K

H-Index

13

Active since

2009

Affiliations

Howard Hughes Medical Institute(Current)

University of California San Diego

Center for Theoretical Biological Physics

University of Illinois Urbana-Champaign

Schrodinger (United States)

William Sinko is an author at Howard Hughes Medical Institute specializing in life sciences, conformational sampling, and drug discovery.

Publications per year

2009–2024

13

Publications

13

Improved Reweighting of Accelerated Molecular Dynamics Simulations for Free Energy Calculation

Yinglong Miao, William Sinko, Levi Pierce et al. · Journal of Chemical Theory and Computation · 2014 · 464 citations · Full text

Natural Sciences, Biochemistry, Biophysics +15

Population Based Reweighting of Scaled Molecular Dynamics

William Sinko, Yinglong Miao, César Augusto F. de Oliveira et al. · The Journal of Physical Chemistry B · 2013 · 112 citations · Full text

Natural Sciences, Biophysics, Computational Biophysics +15

Antibacterial drug leads targeting isoprenoid biosynthesis

Wei Zhu, Yonghui Zhang, William Sinko et al. · Proceedings of the National Academy of Sciences · 2012 · 111 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer’s Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data

Petr Kočiš, Martin Tolar, William Sinko et al. · CNS Drugs · 2017 · 107 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Discovery of Small Molecule Inhibitors of the PH Domain Leucine-Rich Repeat Protein Phosphatase (PHLPP) by Chemical and Virtual Screening

Emma Sierecki, William Sinko, J. Andrew McCammon et al. · Journal of Medicinal Chemistry · 2010 · 78 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

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