William Sinko

Improved Reweighting of Accelerated Molecular Dynamics Simulations for Free Energy Calculation

Yinglong Miao, William Sinko, Levi Pierce et al. · Journal of Chemical Theory and Computation · 2014 · 451 citations · Full text

Population Based Reweighting of Scaled Molecular Dynamics

William Sinko, Yinglong Miao, César Augusto F. de Oliveira et al. · The Journal of Physical Chemistry B · 2013 · 110 citations · Full text

Scaled Molecular Dynamics, Enhanced Conformational Sampling, Engineering +15

Antibacterial drug leads targeting isoprenoid biosynthesis

Wei Zhu, Yonghui Zhang, William Sinko et al. · Proceedings of the National Academy of Sciences · 2012 · 108 citations · Full text

Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer’s Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data

Petr Kočiš, Martin Tolar, William Sinko et al. · CNS Drugs · 2017 · 105 citations · Full text

Discovery of Small Molecule Inhibitors of the PH Domain Leucine-Rich Repeat Protein Phosphatase (PHLPP) by Chemical and Virtual Screening

Emma Sierecki, William Sinko, J. Andrew McCammon et al. · Journal of Medicinal Chemistry · 2010 · 78 citations · Full text

Small Molecule Inhibitors, Drug Target, Molecular Biology +20