Long Noncoding RNAs with Enhancer-like Function in Human Cells

Ulf Andersson Ørom, Thomas Derrien, Malte Beringer, +9

Cell

Transcriptional RegulationRna BiologyNoncoding RnasLong Non-coding RnaGene Expression +3

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

Fan Lai, Matteo Cesaroni, Malte Beringer, +3

Nature

Histone ModificationsChromatinTranscriptional RegulationRna ProcessingChromatin Structure +13

Integrator mediates the biogenesis of enhancer RNAs

Fan Lai, Alessandro Gardini, Anda Zhang, +1

Nature

Enhancer RnasSmall RnaSystems BiologyGene ExpressionRna Processing

A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy

Mei Yang, Liang Chen, Kunchithapadam Swaminathan, +4

Science Advances

Condensin and Repo-Man–PP1 co-operate in the regulation of chromosome architecture during mitosis

Paola Vagnarelli, Damien F. Hudson, Susana A. Ribeiro, +6

Nature Cell Biology

ChromatinChromosome DynamicsDevelopmental BiologyChromosome ArchitectureCell Division +12

Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage

Qiang Shao, Stephanie Herrlinger, Silu Yang, +4

Development

Brain DevelopmentPostnatal MicrocephalyMassive Neuronal DeathNeurological DisorderImmunology +19

Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size

Jian-Fu Chen, Ying Zhang, Jonathan J. Wilde, +3

Nature Communications

Developmental BiologyBrain DevelopmentMedicineStem Cell ResearchBrain Size +10

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

Jian-Fu Chen, Fan Lai, Lee Niswander

Genes & Development

Molecular NeuroscienceDevelopmental BiologyCell RegulationSignaling PathwayMlin41 Promotes Fgf +13

Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination

Fan Lai, Sagar Damle, Karen Ling, +1

Molecular Cell

Transcriptional RegulationEngineeringRna BiologyMolecular BiologyGene Transcription +6

Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line

Zuojun Yue, Ana Xavier Carvalho, Zhenjie Xu, +10

The Journal of Cell Biology

EngineeringGeneticsCell DeathMolecular BiologyCell Proliferation +23