Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery, +3

Nature

Specific Genetic InterferenceNatural SciencesGeneticsRna BiologyMolecular Biology +7

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Rosalind C. Lee, Rhonda Feinbaum, Victor Ambros

Cell

High-Resolution Profiling of Histone Methylations in the Human Genome

Artem Barski, Suresh Cuddapah, Kairong Cui, +6

Cell

Histone ModificationsChromatinHistone MethylationsEpigenetic ChangeGenetics +5

Alternative isoform regulation in human tissue transcriptomes

Eric T. Wang, Rickard Sandberg, Shujun Luo, +6

Nature

Gene RegulationSystems BiologyMedicineFunctional GenomicsGene Expression +2

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Pamela J. Thomas

Nature

Functional GenomicsGene Sequence AnnotationGenome StudyGeneticsComputational Genomics +11

Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs

John L. Rinn, Michael A. Kertesz, Jordon K. Wang, +8

Cell

ChromatinSystems BiologyEngineeringFunctional DemarcationChromatin Remodeling +10

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Bruce Wightman, Ilho Ha, Gary Ruvkun

Cell

Transcriptional RegulationDevelopmental BiologyDevelopmental GeneticsGeneticsGene Regulation +7

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Mitchell Guttman, Ido Amit, Manuel Garber, +17

Nature

ChromatinSystems BiologyLarge Non-coding RnasChromatin StructureChromatin Remodeling +10

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Ahmad M. Khalil, Mitchell Guttman, Maite Huarte, +10

Proceedings of the National Academy of Sciences

RNA Maps Reveal New RNA Classes and a Possible Function for Pervasive Transcription

Philipp Kapranov, Jill Cheng, Sujit Dike, +19

Science

BioinformaticsSystems BiologyPervasive TranscriptionEngineeringUnannotated Rnas +13