Andrea D. Thompson

Pharmacological chaperone for α-crystallin partially restores transparency in cataract models

Leah N. Makley, Kathryn A. McMenimen, Brian T. DeVree et al. · Science · 2015 · 236 citations · Full text

Ocular Disease, Lens Transparency, Molecular Biology +16

Binding of a Small Molecule at a Protein–Protein Interface Regulates the Chaperone Activity of Hsp70–Hsp40

Susanne Wisén, Eric B. Bertelsen, Andrea D. Thompson et al. · ACS Chemical Biology · 2010 · 161 citations

Hsp70-hsp40 Complex Assembly, Protein Assembly, Molecular Biology +17

Imbalance of Hsp70 family variants fosters tau accumulation

Umesh K. Jinwal, Elias Akoury, Jose F. Abisambra et al. · The FASEB Journal · 2012 · 113 citations · Full text

Cysteine Reactivity Distinguishes Redox Sensing by the Heat-Inducible and Constitutive Forms of Heat Shock Protein 70

Yoshinari Miyata, Jennifer N. Rauch, Umesh K. Jinwal et al. · Chemistry & Biology · 2012 · 92 citations · Full text

Protein Chemistry, Reductive Stress, Biochemistry +8

Spatial and Functional Distribution of <i>MYBPC3</i> Pathogenic Variants and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy

Adam Helms, Andrea D. Thompson, Amelia A. Glazier et al. · Circulation Genomic and Precision Medicine · 2020 · 91 citations · Full text