Leah N. Makley

Pharmacological chaperone for α-crystallin partially restores transparency in cataract models

Leah N. Makley, Kathryn A. McMenimen, Brian T. DeVree et al. · Science · 2015 · 236 citations · Full text

Ocular Disease, Lens Transparency, Molecular Biology +16

BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins

Jennifer N. Rauch, Eric Tse, Rebecca Freilich et al. · Journal of Molecular Biology · 2016 · 136 citations · Full text

Protein Function, Protein Assembly, Biochemistry +10

Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity

Alex M. Jaeger, Leah N. Makley, Jason E. Gestwicki et al. · Journal of Biological Chemistry · 2014 · 71 citations · Full text

Identification of dihydropyridines that reduce cellular tau levels

Christopher G. Evans, Umesh K. Jinwal, Leah N. Makley et al. · Chemical Communications · 2010 · 41 citations

Pharmacological Tuning of Heat Shock Protein 70 Modulates Polyglutamine Toxicity and Aggregation

Sidhartha M. Chafekar, Susanne Wisén, Andrea D. Thompson et al. · ACS Chemical Biology · 2012 · 35 citations · Full text

Molecular Pharmacology, Protein Function, Biochemistry +14