Bram van den Broek

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Guotai Xu, J. Ross Chapman, Inger Brandsma et al. · Nature · 2015 · 583 citations · Full text

Chromatin, Genome Instability, Parp Inhibition +6

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Ewa Gogola, Alexandra A. Duarte, Julian R. de Ruiter et al. · Cancer Cell · 2018 · 379 citations · Full text

Parg Restores Parylation, Selective Loss, Medicine +4

3D genomics across the tree of life reveals condensin II as a determinant of architecture type

Claire Hoencamp, Olga Dudchenko, Ahmed M.O. Elbatsh et al. · Science · 2021 · 290 citations · Full text

Structural Bioinformatics, Genetics, Molecular Biology +25

Facilitated diffusion with DNA coiling

Michael A. Lomholt, Bram van den Broek, Svenja-Marei J. Kalisch et al. · Proceedings of the National Academy of Sciences · 2009 · 200 citations · Full text

Dna Nanotechnology, Coiled-coil Drug Delivery, Microscopy +15

How DNA coiling enhances target localization by proteins

Bram van den Broek, Michael A. Lomholt, Svenja-Marei Kalisch et al. · Proceedings of the National Academy of Sciences · 2008 · 200 citations · Full text