Charles J. Murphy

Chromosomal instability drives metastasis through a cytosolic DNA response

Samuel F. Bakhoum, Bryan Ngo, Ashley M. Laughney et al. · Nature · 2018 · 1.5K citations · Full text

Chromatin, Genome Instability, Chromosomal Instability +3

High-fructose corn syrup enhances intestinal tumor growth in mice

Marcus D. Goncalves, Changyuan Lu, Jordan Tutnauer et al. · Science · 2019 · 363 citations

Gastrointestinal Oncology, Medicine, High-fructose Corn Syrup +11

Fenofibrate prevents skeletal muscle loss in mice with lung cancer

Marcus D. Goncalves, Seo‐Kyoung Hwang, Chantal Pauli et al. · Proceedings of the National Academy of Sciences · 2018 · 122 citations · Full text

Ketone Production, Metabolic Remodeling, Caloric Restriction +25

R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine

Teng Han, Emma M. Schatoff, Charles J. Murphy et al. · Nature Communications · 2017 · 120 citations · Full text

A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification

Christopher M. Browne, Baishan Jiang, Scott B. Ficarro et al. · Journal of the American Chemical Society · 2018 · 89 citations · Full text

Drug Target, Chemoproteomic Strategy, Enrichment Reagents +16