Teng Han

Optimized base editors enable efficient editing in cells, organoids and mice

María Paz Zafra, Emma M. Schatoff, Alyna Katti et al. · Nature Biotechnology · 2018 · 351 citations

Life Sciences, Cell Biology, Molecular Genetics +12

Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets

Fanying Tang, Duo Xu, Shangqian Wang et al. · Science · 2022 · 270 citations · Full text

Medicine, Molecular Biology, Oncology +17

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

Brisa Palikuqi, Duc-Huy T. Nguyen, Ge Li et al. · Nature · 2020 · 256 citations · Full text

Life Sciences, Bioengineering, Cell Biology +12

Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer

Kevin P. O’Rourke, Evangelia Loizou, Geulah Livshits et al. · Nature Biotechnology · 2017 · 238 citations · Full text

Medicine, Cancer Biology, Oncology +16

An <i>In Vivo Kras</i> Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants

María Paz Zafra, Marie J. Parsons, Jangkyung Kim et al. · Cancer Discovery · 2020 · 137 citations · Full text

Medicine, Genetics, Oncology +17