Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease

Malin von Otter, Sara Landgren, Staffan Nilsson, +11

BMC Medical Genetics

Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production

Line S. Reinert, Ahmad Rashidi, Diana Tran, +18

Journal of Clinical Investigation

Viral PathogenesisImmunologyCell DeathImmune RegulationSimplex Encephalitis +17

Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract

Malin von Otter, Sara Landgren, Staffan Nilsson, +14

Mechanisms of Ageing and Development

Alzheimer's DiseaseOphthalmologyDementiaVascular DementiaNrf2-encoding Nfe2l2 +8

HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection

Chiranjeevi Bodda, Line S. Reinert, Stefanie Fruhwürth, +13

The Journal of Experimental Medicine

Hsv1 MutantsViral PathogenesisImmunologyInnate ImmunityHsv1 δDub +21

Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage

Petra Bergström, Heléne C. Andersson, Yue Gao, +5

Neuropharmacology

InflammationReductive StressSignal TransductionBiochemistryTransient Sulforaphane Stimulation +12

Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

Petra Bergström, Lotta Agholme, Faisal Hayat Nazir, +16

Scientific Reports

App ProcessingBrain DevelopmentCerebral OrganoidNeurochemical BiomarkersAmyloid Precursor Protein +20

Association of NFE2L2 and KEAP1 haplotypes with amyotrophic lateral sclerosis

Petra Bergström, Malin von Otter, Staffan Nilsson, +5

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisSporadic AlsNeurological DisorderGenetics +9

Repeated Nrf2 stimulation using sulforaphane protects fibroblasts from ionizing radiation

Sherin T. Mathew, Petra Bergström, Ola Hammarsten

Toxicology and Applied Pharmacology

Radiation OncologySignal TransductionRadiation EffectRedox BiologyNrf2 Stimulation +7

Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons

Tuğçe Munise Şatır, Faisal Hayat Nazir, Dzeneta Vizlin‐Hodzic, +6

Scientific Reports

Partial reduction of amyloid β production by β-secretase inhibitors does not decrease synaptic transmission

Tuğçe Munise Şatır, Lotta Agholme, Anna Karlsson, +5

Alzheimer s Research & Therapy