Dilinie P. Fernando

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1<i>H</i>-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy

Kimberly O. Cameron, Daniel W. Kung, Amit S. Kalgutkar et al. · Journal of Medicinal Chemistry · 2016 · 115 citations · Full text

Renal Inflammation, Pharmacotherapy, Insulin Signaling +19

New Practical Synthesis of Indazoles via Condensation of <i>o</i>-Fluorobenzaldehydes and Their <i>O</i>-Methyloximes with Hydrazine

K. A. LUKIN, Margaret C. Hsu, Dilinie P. Fernando et al. · The Journal of Organic Chemistry · 2006 · 106 citations

Derivative (Chemistry), Benzonitrile Intermediate, Major E-isomers +8

A General Method for the Synthesis of Unsymmetrically Substituted Ureas via Palladium-Catalyzed Amidation

Brian Kotecki, Dilinie P. Fernando, Anthony R. Haight et al. · Organic Letters · 2009 · 83 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +13

Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose

Kentaro Futatsugi, Aaron Smith, Meihua Tu et al. · Journal of Medicinal Chemistry · 2020 · 69 citations · Full text

Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate

Samit K. Bhattacharya, Kim Andrews, Ramsay E. Beveridge et al. · ACS Medicinal Chemistry Letters · 2014 · 67 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +10