Lilli Anselm

Systematic Investigation of Halogen Bonding in Protein–Ligand Interactions

Leo A. Hardegger, Bernd Kuhn, Beat Spinnler et al. · Angewandte Chemie International Edition · 2010 · 486 citations

Life Sciences, Chemistry, Medicinal Chemistry +15

Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

Leo A. Hardegger, Bernd Kuhn, Beat Spinnler et al. · ChemMedChem · 2011 · 128 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds

Hans Hilpert, Harald Mauser, Roland Humm et al. · Journal of Medicinal Chemistry · 2013 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and<i>Trypanosoma brucei</i>Inhibitors

Maude Giroud, Uwe Dietzel, Lilli Anselm et al. · Journal of Medicinal Chemistry · 2018 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} as a clinical candidate

Lilli Anselm, David W. Banner, Jörg Benz et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +5