Jack Bartram

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

Sara Ghorashian, Anne Marijn Kramer, Shimobi Onuoha et al. · Nature Medicine · 2019 · 644 citations · Full text

Life Sciences, Immunology, Pediatrics +16

Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukaemia; a EuroClonality-NGS validation study

Monika Brüggemann, Michaela Kotrová, Henrik Knecht et al. · Leukemia · 2019 · 261 citations · Full text

Medicine, Bioinformatics, Hematology +17

Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia

Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi et al. · Science Translational Medicine · 2022 · 184 citations · Full text

Life Sciences, Biotechnology, Immunology +17

Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia

David O’Connor, Amir Enshaei, Jack Bartram et al. · Journal of Clinical Oncology · 2017 · 169 citations · Full text

Life Sciences, Genetics, Oncology +17

Targeting acute myeloid leukemia by drug-induced c-MYB degradation

Vanessa Walf-Vorderwülbecke, Kerra Pearce, Tony Brooks et al. · Leukemia · 2017 · 113 citations · Full text

Medicine, Oncology, Pharmacology +14