Tomohiko Ishihara

Increased cytoplasmic<i>TARDBP</i>mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43

Akihide Koyama, Akihiro Sugai, Taisuke Kato et al. · Nucleic Acids Research · 2016 · 109 citations · Full text

Synaptic Signaling, Social Sciences, Transcriptional Regulation +18

Alteration of POLDIP3 Splicing Associated with Loss of Function of TDP-43 in Tissues Affected with ALS

Atsushi Shiga, Tomohiko Ishihara, Akinori Miyashita et al. · PLoS ONE · 2012 · 89 citations · Full text

Tissues Affected, Pathology, Molecular Biology +17

Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis

Ryosuke Oki, Yuishin Izumi, Koji Fujita et al. · JAMA Neurology · 2022 · 78 citations · Full text

Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis

Tomohiko Ishihara, Yuko Ariizumi, Atsushi Shiga et al. · Human Molecular Genetics · 2013 · 73 citations · Full text

Neurological Disorder, Molecular Biology, Neurology +16

Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker of myogenic degeneration in amyotrophic lateral sclerosis and various conditions

Fumiaki Mori, Mari Tada, Tomoya Kon et al. · Acta Neuropathologica Communications · 2019 · 66 citations · Full text