Yinquan Fang

NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression

Shanshan Li, Yiming Sun, Mengmeng Song et al. · JCI Insight · 2021 · 314 citations · Full text

Medicine, Neuroscience, Psychiatry +17

Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice

Shanshan Li, Yinquan Fang, Yihe Zhang et al. · Cell Reports · 2022 · 217 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage

Wei Yao, QianQian Miao, Qian Zhang et al. · Nature Neuroscience · 2023 · 149 citations

Life Sciences, Neurobiology, Neuroscience +12

Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT2BR/β-arrestin2 pathway

Yinquan Fang, Xiao Ding, Yihe Zhang et al. · Journal of Neuroinflammation · 2022 · 92 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Opposing functions of β-arrestin 1 and 2 in Parkinson’s disease via microglia inflammation and Nprl3

Yinquan Fang, Qingling Jiang, Shanshan Li et al. · Cell Death and Differentiation · 2021 · 82 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17