Yinquan Fang

NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression

Shanshan Li, Yiming Sun, Mengmeng Song et al. · JCI Insight · 2021 · 285 citations · Full text

Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice

Shanshan Li, Yinquan Fang, Yihe Zhang et al. · Cell Reports · 2022 · 198 citations · Full text

Inflammation, A1 Inductors, A1-like Astrocytes +14

Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage

Wei Yao, QianQian Miao, Qian Zhang et al. · Nature Neuroscience · 2023 · 120 citations

Energy Metabolism, Glycosylation, Biochemistry +14

Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT2BR/β-arrestin2 pathway

Yinquan Fang, Xiao Ding, Yihe Zhang et al. · Journal of Neuroinflammation · 2022 · 81 citations · Full text

Opposing functions of β-arrestin 1 and 2 in Parkinson’s disease via microglia inflammation and Nprl3

Yinquan Fang, Qingling Jiang, Shanshan Li et al. · Cell Death and Differentiation · 2021 · 79 citations · Full text

Microglia Inflammation, Immunology, Immune Regulation +20