Stella Karsten

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Torkild Visnes, Armando Cázares‐Körner, Wenjing Hao et al. · Science · 2018 · 233 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nadilly Bonagas, Nina Gustafsson, Martin Henriksson et al. · Nature Cancer · 2022 · 105 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function

Maurice Michel, Carlos Benitéz‐Buelga, Patricia A. Calvo et al. · Science · 2022 · 75 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition

Lars Bräutigam, Linda Pudelko, Ann‐Sofie Jemth et al. · Cancer Research · 2016 · 60 citations

Medicine, Oncology, Pharmacology +17

Targeting OGG1 arrests cancer cell proliferation by inducing replication stress

Torkild Visnes, Armando Cázares‐Körner, Kumar Sanjiv et al. · Nucleic Acids Research · 2020 · 59 citations · Full text

Medicine, Cancer Biology, Oncology +14