Rukhsana T. Mohammed

Optimization of Monocarboxylate Transporter 1 Blockers through Analysis and Modulation of Atropisomer Interconversion Properties

Simon D. Guile, John R. Bantick, Martin Cooper et al. · Journal of Medicinal Chemistry · 2006 · 67 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +15

Potent blockers of the monocarboxylate transporter MCT1: Novel immunomodulatory compounds

Simon D. Guile, John R. Bantick, David R. Cheshire et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 48 citations · Full text

Molecular Physiology, Polymer-drug Conjugate, Medicine +6

Cyclization of Lithiated Pyridine and Quinoline Carboxamides:  Synthesis of Partially Saturated Pyrrolopyridines and Spirocyclic β-Lactams

Jonathan Clayden, Stuart D. Hamilton, Rukhsana T. Mohammed · Organic Letters · 2005 · 43 citations

Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists—discovery of AZD1981

Tim Luker, Roger V. Bonnert, Steve Brough et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +9

Switching between agonists and antagonists at CRTh2 in a series of highly potent and selective biaryl phenoxyacetic acids

Tim Luker, Roger V. Bonnert, Jerzy A. Schmidt et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 10 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +7