Jonggul Kim

A dynamic hydrophobic core orchestrates allostery in protein kinases

Jonggul Kim, Lalima G. Ahuja, Fa-An Chao et al. · Science Advances · 2017 · 111 citations · Full text

Protein Chemistry, Hydrophobic Core, Protein Kinase A +14

NMR mapping of protein conformational landscapes using coordinated behavior of chemical shifts upon ligand binding

Alessandro Cembran, Jonggul Kim, Jiali Gao et al. · Physical Chemistry Chemical Physics · 2014 · 65 citations · Full text

Synchronous Opening and Closing Motions Are Essential for cAMP-Dependent Protein Kinase A Signaling

Atul Srivastava, Leanna R. McDonald, Alessandro Cembran et al. · Structure · 2014 · 64 citations · Full text

Molecular Physiology, Signal Transduction, Signaling Pathway +10

Globally correlated conformational entropy underlies positive and negative cooperativity in a kinase’s enzymatic cycle

Yingjie Wang, Jonggul Kim, Geoffrey Li et al. · Nature Communications · 2019 · 54 citations · Full text

Conformational Entropy, Biophysical Modeling, Conformational Entropy Underlies +16

ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy

Cristina Olivieri, Geoffrey Li, Yingjie Wang et al. · Science Advances · 2022 · 51 citations · Full text

Conformational Entropy, Protein Assembly, Biochemistry +14