Sophie Franklin

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

Michał Mielcarek, Christian Landles, Andreas Weiss et al. · PLoS Biology · 2013 · 166 citations · Full text

SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease

Michał Mielcarek, Caroline Benn, Sophie Franklin et al. · PLoS ONE · 2011 · 159 citations · Full text

Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease

Michał Mielcarek, Linda Inuabasi, Marie K. Bondulich et al. · PLoS Genetics · 2014 · 91 citations · Full text

Heart Failure, Alzheimer's Disease, Mouse Models +16

mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington’s Disease

Anne Ast, Alexander Buntru, Franziska Schindler et al. · Molecular Cell · 2018 · 75 citations · Full text

Neurodegenerative Diseases, Developmental Biology, Huntington ’ +9

HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy

Michał Mielcarek, Marta Toczek, Cleo J. L. M. Smeets et al. · PLoS Genetics · 2015 · 63 citations · Full text

Hd Mouse Models, Muscle Function, Cytoskeleton +16