DIFFERENTIAL EFFECTS BETWEEN MARIMASTAT, A TNF-α CONVERTING ENZYME INHIBITOR, AND ANTI-TNF-α ANTIBODY ON MURINE MODELS FOR SEPSIS AND ARTHRITIS

Fumio Tsuji, Kenji Oki, Akihiko Okahara, +5

Cytokine

InflammationRheumatologyAnti-inflammatoryMedicineImmune Regulation +7

SA13353 (1-[2-(1-Adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea) inhibits TNF-α production through the activation of capsaicin-sensitive afferent neurons mediated via transient receptor potential vanilloid 1 in vivo

Masaaki Murai, Fumio Tsuji, M Nose, +6

European Journal of Pharmacology

Signal TransductionMolecular PhysiologySynaptic SignalingMolecular NeuroscienceMedicine +13

Stereochemistry of the Conversion of γ-Substituted (<i>E</i>)-Vinylsulfones to the Corresponding Allylsulfones. Determination of the Relative Degree of “Syn-Effect”

Katsuhiko Inomata, Takaki Hirata, Hiroshi Suhara, +3

Chemistry Letters

EngineeringHeterocyclicOrganic Chemistryγ-Substituted VinylsulfonesRelative Degree +9

NMR study of a heterochiral DNA: stable Watson-Crick-type base-pairing between the enantiomeric residues

Hidehito Urata, Y. Ueda, Hiroshi Suhara, +2

Journal of the American Chemical Society

Molecular SciencesBioorganic ChemistryHeterochiral DnaBiochemistryStable Watson-crick-type Base-pairing +13

Effectiveness of Calcium Preparation to Control Microbial Growth in Food.

Kenji Isshiki, Hiroshi Suhara, Kenji Mizuuchi, +1

NIPPON SHOKUHIN KOGYO GAKKAISHI

Synthesis and Pharmacological Activities of Novel Cyclic Disulfide and Cyclic Sulfide Derivatives as Hepatoprotective Agents.

Susumu Ito, Hiroshi Suhara, Keizo Tabashi, +1

Chemical and Pharmaceutical Bulletin

Medicinal ChemistryNine-membered Cyclic DisulfidesPharmaceutical ScienceBiochemistryCorresponding Dithiol Derivatives +13

Photoinduced Masked-Formylation of Vinylsulfone Derivatives with 1,3-Dioxolane. Application to the Synthesis of 3,4-Disubstituted Pyrroles

Katsuhiko Inomata, Hiroshi Suhara, Hideki Kinoshita, +1

Chemistry Letters

Chemical EngineeringDerivativesEngineeringPhotochemistryHeterocyclic +12

Synthesis and biological evaluation of N-mercaptoacylcysteine derivatives as leukotriene A4 hydrolase inhibitors

Hiroshi Enomoto, Yuko Morikawa, Yurika Miyake, +6

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMolecular PharmacologyBiochemistryMedicineNatural Sciences +7

New Ethacrynic Acid Derivatives as Potent Cytoskeletal Modulators in Trabecular Meshwork Cells

Atsushi Shimazaki, Hiroshi Suhara, Masaki Ichikawa, +6

Biological and Pharmaceutical Bulletin

Tissue EngineeringOcular DiseaseEthacrynic AcidEngineeringTrabecular Meshwork Cells +21