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Lara Planas‐Paz, Vanessa Orsini, Luke Boulter, +30

Nature Cell Biology

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A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples

Sven Schuierer, Walter Carbone, Judith Knehr, +4

BMC Genomics

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency

Michael Bidinosti, Paolo Botta, Sebastian Krüttner, +17

Science

Synaptic TransmissionNeurochemical BiomarkersRapamycin Complex 1Synaptic SignalingSocial Sciences +23

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

Rowena DeJesus, Francesca Moretti, Gregory McAllister, +21

eLife

GeneticsCrispr-mediated GenomeMolecular BiologyEpigeneticsFunctional Crispr +14

Fast and highly sensitive full-length single-cell RNA sequencing using FLASH-seq

Vincent Hahaut, Dinko Pavlinić, Walter Carbone, +7

Nature Biotechnology

GeneticsTranscriptomics TechnologyPresent Flash-seqGenomicsHigh Throughput Sequencing +17

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy

Christoph Potting, Christophe Crochemore, Francesca Moretti, +16

Proceedings of the National Academy of Sciences

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi

Annemarie Voorberg-van der Wel, Guglielmo Roma, Devendra Gupta, +15

eLife

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

Nathan T. Ross, Felix Lohmann, Seth Carbonneau, +39

Nature Chemical Biology

Transcriptional RegulationMedicineCancer Cell BiologyDruggable NodeCpsf3-dependent Pre-mrna Processing +7

Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis

Rosemarie Ungricht, Laure Guibbal, Marie-Christine Lasbennes, +11

Cell stem cell

Renal FunctionDevelopmental BiologyEngineeringMedicineGenetics +9

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

Melusine Bleu, Swann Gaulis, Rui Lopes, +16

Nature Communications