Tobias Kanacher

A Systematic Evaluation of the Use of Physiologically Based Pharmacokinetic Modeling for Cross-Species Extrapolation

Christoph Thiel, Sebastian Schneckener, Ahmed Ghallab et al. · Journal of Pharmaceutical Sciences · 2014 · 111 citations

Physiologically Based Pharmacokinetics, Pharmacokinetic Modeling, Health Sciences +10

Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens

Daniel Moj, Nina Hanke, Hannah Britz et al. · The AAPS Journal · 2016 · 42 citations

Drug Interactions, Therapeutic Drug Monitoring, Pharmacokinetic Modeling +9

A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug–Drug–Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine

Tobias Kanacher, Andreas Lindauer, Enrica Mezzalana et al. · Pharmaceutics · 2020 · 25 citations · Full text

CYP3A4‐mediated effects of rifampicin on the pharmacokinetics of vilaprisan and its UGT1A1‐mediated effects on bilirubin glucuronidation in humans

Niladri Chattopadhyay, Tobias Kanacher, Manuela Casjens et al. · British Journal of Clinical Pharmacology · 2018 · 22 citations · Full text