Sebastian Schneckener

A Systematic Evaluation of the Use of Physiologically Based Pharmacokinetic Modeling for Cross-Species Extrapolation

Christoph Thiel, Sebastian Schneckener, Ahmed Ghallab et al. · Journal of Pharmaceutical Sciences · 2014 · 111 citations

Physiologically Based Pharmacokinetics, Pharmacokinetic Modeling, Health Sciences +10

Prediction of Oral Bioavailability in Rats: Transferring Insights from in Vitro Correlations to (Deep) Machine Learning Models Using in Silico Model Outputs and Chemical Structure Parameters

Sebastian Schneckener, Sergio Grimbs, Jessica Hey et al. · Journal of Chemical Information and Modeling · 2019 · 96 citations

Using Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic Modeling

Michaela Meyer, Sebastian Schneckener, Bernd Ludewig et al. · Drug Metabolism and Disposition · 2012 · 94 citations

ProClust: improved clustering of protein sequences with an extendedgraph-based approach

P. Pipenbacher, Alexander Schliep, Sebastian Schneckener et al. · Bioinformatics · 2002 · 89 citations

Prediction of Human Pharmacokinetics From Chemical Structure: Combining Mechanistic Modeling with Machine Learning

Andrea Grüber, Florian Führer, Stephan Menz et al. · Journal of Pharmaceutical Sciences · 2023 · 29 citations · Full text

Combining Mechanistic Modeling, Physiologically Based Pharmacokinetics, Pharmacokinetic Modeling +10