Hisao Hirota

Loss of a gp130 Cardiac Muscle Cell Survival Pathway Is a Critical Event in the Onset of Heart Failure during Biomechanical Stress

Hisao Hirota, Ju Chen, Ulrich A. K. Betz et al. · Cell · 1999 · 661 citations · Full text

Life Sciences, Cell Biology, Physiology +13

Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.

Hisao Hirota, Kiyoshi Yoshida, T. Kishimoto et al. · Proceedings of the National Academy of Sciences · 1995 · 505 citations

Life Sciences, Cardiology, Physiology +17

Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors.

Nobuyuki Udagawa, N. Takahashi, Takashi Katagiri et al. · The Journal of Experimental Medicine · 1995 · 419 citations · Full text

Life Sciences, Cell Biology, Immunology +11

AMP-Activated Protein Kinase Protects Cardiomyocytes against Hypoxic Injury through Attenuation of Endoplasmic Reticulum Stress

Kazuo Terai, Yoshimune Hiramoto, Mitsuru Masaki et al. · Molecular and Cellular Biology · 2005 · 352 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma.

Hisao Hirota, Hiroshi Kiyama, Tadamitsu Kishimoto et al. · The Journal of Experimental Medicine · 1996 · 321 citations · Full text

Medicine, Neurobiology, Neuroscience +17