Julie J. Purkal - Concepedia

Author

Julie J. Purkal

Pfizer (United States)ORCID

Also Known As

J. Purkal, Julie J Purkal, Julie J. Purkal, Julie Purkal, Purkal, Julie

Publications

588

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)AbbVie (United States)

About

Julie J. Purkal is an author at Pfizer (United States) specializing in medicine, pharmacology, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	193
2	Biochemistry	3	3	156
3	Health Sciences	2	2	74
4	Natural Sciences	2	2	119
5	Cell Biology	1	1	37

Julie J. Purkal

Publications

571

Citations

H-Index

Page 1

	Year	Citations
5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-Mediated Apoptosis Sha Jin, Dan Cojocari, Julie J. Purkal, Clinical Cancer Research	2020	187
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2) Kentaro Futatsugi, Daniel W. Kung, Suvi T. M. Orr, Journal of Medicinal Chemistry Combinatorial ChemistryLipid AnalysisMedicinal ChemistryBioorganic ChemistryLipid Synthesis	2015	80
Targeting diacylglycerol acyltransferase 2 for the treatment of nonalcoholic steatohepatitis Neeta B. Amin, Santos Carvajal‐Gonzalez, Julie J. Purkal, Science Translational Medicine	2019	68
Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition William P. Esler, Gregory J. Tesz, Marc K. Hellerstein, Science Translational Medicine	2019	62
Application of LDH assay for therapeutic efficacy evaluation of ex vivo tumor models Megan Cox, Rita Mendes, Fernanda Silva, Scientific Reports	2021	51
Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family Kim Huard, J Gosset, Justin I. Montgomery, Journal of Medicinal Chemistry Pharmaceutical ScienceCompound 4ASodium-coupled Citrate TransporterCellular PharmacologyPharmacotherapy	2016	39
The Hepatoselective Glucokinase Activator PF-04991532 Ameliorates Hyperglycemia without Causing Hepatic Steatosis in Diabetic Rats Derek M. Erion, Amanda L. Lapworth, Paul A. Amor, PLoS ONE GlycobiologyGlucose HomeostasisFatty Liver DiseaseInsulin SignalingOxidative Stress	2014	37
Pevonedistat and azacitidine upregulate NOXA (PMAIP1) to increase sensitivity to venetoclax in preclinical models of acute myeloid leukemia Dan Cojocari, Brianna N. Smith, Julie J. Purkal, Haematologica Mixed-phenotype Acute LeukemiaImmunologyPharmacotherapyTumor BiologyMyeloid Neoplasia	2021	37
Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile Kentaro Futatsugi, Kim Huard, Daniel W. Kung, MedChemComm	2016	10

Page 1