Simona Sestito

Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells

Simona Daniele, Barbara Costa, Elisa Zappelli et al. · Scientific Reports · 2015 · 93 citations · Full text

Memantine prodrug as a new agent for Alzheimer’s Disease

Simona Sestito, Simona Daniele, Deborah Pietrobono et al. · Scientific Reports · 2019 · 80 citations · Full text

Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease

Ziwei Chen, Maria Digiacomo, Yalin Tu et al. · European Journal of Medicinal Chemistry · 2016 · 68 citations

Medicinal Chemistry, Alzheimer's Disease, Biochemistry +8

Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?

Simona Sestito, Letizia Pruccoli, Massimiliano Runfola et al. · European Journal of Medicinal Chemistry · 2019 · 61 citations

Combinatorial Chemistry, Medicinal Chemistry, H2s-donor Hybrids +8

Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis

Massimiliano Runfola, Simona Sestito, Lorenza Bellusci et al. · European Journal of Medicinal Chemistry · 2019 · 54 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Target +12