Catherine R. O’Riordan

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Seng H. Cheng, Richard J. Gregory, John Marshall et al. · Cell · 1990 · 1.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

PEGylation of Adenovirus with Retention of Infectivity and Protection from Neutralizing Antibody in Vitro and in Vivo

Catherine R. O’Riordan, Amy Lachapelle, Cristina Delgado et al. · Human Gene Therapy · 1999 · 409 citations

Life Sciences, Immunology, Molecular Biology +14

CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy

Marco A. Passini, Jie Bu, Eric M. Roskelley et al. · Journal of Clinical Investigation · 2010 · 295 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Analytical Ultracentrifugation as an Approach to Characterize Recombinant Adeno-Associated Viral Vectors

Brenda Burnham, Shelley Nass, Elton Kong et al. · Human Gene Therapy Methods · 2015 · 150 citations

Life Sciences, Biology, Biotechnology +16

Universal Method for the Purification of Recombinant AAV Vectors of Differing Serotypes

Shelley Nass, Maryellen Mattingly, Denise Woodcock et al. · Molecular Therapy — Methods & Clinical Development · 2017 · 141 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +14