Andrew M. Griffin - Concepedia

Author

Andrew M. Griffin

Also Known As

A. GRIFFIN, A. Griffin, A. M. GRIFFIN, A. M. Griffin, Andrew Griffin, Andrew M Griffin, Andrew M. Griffin, Griffin, Andrew M.

Publications

592

Citations

H-Index

Concepts

All Affiliations

AstraZeneca (Canada)Florey Institute of Neuroscience and Mental Health Precision for Medicine (United States)Praxis (United States)AstraZeneca (United States)

About

Andrew M. Griffin is an author at AstraZeneca (Canada) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	179
2	Natural Sciences	3	3	48
3	Engineering	2	2	37
4	Health Sciences	1	1	13
5	Social Sciences	1	1	27

Andrew M. Griffin

Publications

501

Citations

H-Index

Page 1

	Year	Citations
Combined Targeting of the BRD4–NUT–p300 Axis in NUT Midline Carcinoma by Dual Selective Bromodomain Inhibitor, NEO2734 Chevaun D. Morrison-Smith, Tatiana M. Knox, Ivona Filic, Molecular Cancer Therapeutics	2020	83
Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules Tim Luker, Lilian Alcaraz, Kamaldeep K. Chohan, Bioorganic & Medicinal Chemistry Letters Vivo Toxicology OutcomesPreclinical Drug EvaluationPharmacological StudyMedicineImmunology	2011	57
Preclinical Pharmacology of AZD2327: A Highly Selective Agonist of the δ-Opioid Receptor Thomas J. Hudzik, Carla Maciag, Mark A. Smith, Journal of Pharmacology and Experimental Therapeutics	2011	54
Safety, Pharmacokinetics, and Pharmacodynamics Study in Healthy Subjects of Oral NEO6860, a Modality Selective Transient Receptor Potential Vanilloid Subtype 1 Antagonist W. A. Brown, Richard L. Leff, Andrew M. Griffin, Journal of Pain Oral Neo6860Healthy SubjectsPharmacodynamics StudyFunctional SelectivityMedicine	2017	48
Discovery of the First Orally Available, Selective K<sub>Na</sub>1.1 Inhibitor: <i>In Vitro</i> and <i>In Vivo</i> Activity of an Oxadiazole Series Andrew M. Griffin, Kristopher M. Kahlig, Robert J. Hatch, ACS Medicinal Chemistry Letters	2021	48
β-Tetraphosphorus pentasulphide Andrew M. Griffin, George M. Sheldrick Acta Crystallographica Section B	1975	31
Discovery of Spirofused Piperazine and Diazepane Amides as Selective Histamine-3 Antagonists with in Vivo Efficacy in a Mouse Model of Cognition Dean G. Brown, Peter R Bernstein, Andrew M. Griffin, Journal of Medicinal Chemistry Diazepane AmidesDrug TargetPsychopharmacologyPharmacotherapyNew Series	2014	27
The novel persistent sodium current inhibitor PRAX‐562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers Kristopher M. Kahlig, Liam Scott, Robert J. Hatch, Epilepsia	2022	27
Reductive cleavage as a route to carbohydrate enolates. Applications to the synthesis of C-linked disaccharides Hayley Binch, Andrew M. Griffin, Sabine Schwidetzky, Journal of the Chemical Society Chemical Communications C-disaccharide DerivativesBiosynthesisBioorganic ChemistryEngineeringBiochemistry	1995	24
Tricyclic β-lactams: Total synthesis and antibacterial activity of 5α-methoxyethyl and 5α-hydroxyethyl trinems Stephen Hanessian, Andrew M. Griffin, Michael J. Rozema Bioorganic & Medicinal Chemistry Letters Bioorganic ChemistryMedicineAntibacterial ActivityTricyclic β-LactamsTotal Synthesis	1997	23

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