Jan Tykvart

Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

Martin Klíma, Dániel J. Tóth, R. Hexnerova et al. · Scientific Reports · 2016 · 97 citations · Full text

Proteinlipid Interaction, Phosphatidylinositol 4-Kinase Beta, Autophagy +18

Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery

Jan Tykvart, Jiří Schimer, Jitka Bařinková et al. · Bioorganic & Medicinal Chemistry · 2014 · 58 citations · Full text

Specific Drug Targeting, Medicinal Chemistry, Versatile Tools +10

Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II

Jan Tykvart, Pavel Šácha, Cyril Bařinka et al. · Protein Expression and Purification · 2011 · 42 citations · Full text

Protein Chemistry, Protein Expression, Biochemistry +8

iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties

Pavel Šácha, Tomáš Knedlík, Jiří Schimer et al. · Angewandte Chemie International Edition · 2016 · 39 citations · Full text

Comparative analysis of monoclonal antibodies against prostate-specific membrane antigen (PSMA)

Jan Tykvart, Václav Navrátil, František Sedlák et al. · The Prostate · 2014 · 35 citations