Yoshi Nara

Discovery of a Thieno[2,3- <i>d</i> ]pyrimidine-2,4-dione Bearing a <i>p</i> -Methoxyureidophenyl Moiety at the 6-Position:  A Highly Potent and Orally Bioavailable Non-Peptide Antagonist for the Human Luteinizing Hormone-Releasing Hormone Receptor

Satoshi Sasaki, Nobuo Cho, Yoshi Nara et al. · Journal of Medicinal Chemistry · 2002 · 161 citations · Full text

Discovery of [<i>cis</i>-3-({(5<i>R</i>)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1<i>H</i>-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5<i>H</i>)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist

Mitsunori Kono, Atsuko Ochida, Tsuneo Oda et al. · Journal of Medicinal Chemistry · 2018 · 62 citations

Pharmacotherapy, Pharmaceutical Chemistry, Pre-clinical Pharmacology +16

Design, Synthesis, and Biological Evaluation of Retinoic Acid-Related Orphan Receptor γt (RORγt) Agonist Structure-Based Functionality Switching Approach from In House RORγt Inverse Agonist to RORγt Agonist

Tomoya Yukawa, Yoshi Nara, Mitsunori Kono et al. · Journal of Medicinal Chemistry · 2019 · 24 citations · Full text

Immunology, Immunotherapeutics, Molecular Pharmacology +17

CCR5 antagonists as anti-HIV-1 agents. Part 2: Synthesis and biological evaluation of N-[3-(4-benzylpiperidin-1-yl)propyl]-N,N′-diphenylureas

Shinichi Imamura, Osamu Kurasawa, Yoshi Nara et al. · Bioorganic & Medicinal Chemistry · 2004 · 17 citations

Medicine, Immunology, Antiviral Drug Development +7