Lesley Jardine

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.

Robert te Poele, Andrei L. Okorokov, Lesley Jardine et al. · PubMed · 2002 · 646 citations

Lifespan Extension, Tumor Biology, Genome Instability +15

Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives.

Jeffrey L. Cummings, Brian Ethell, Lesley Jardine et al. · PubMed · 2003 · 82 citations

Gastrointestinal Pharmacology, Intrinsic Drug Resistance, Cancer Biology +18

Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover

Nicolas Dumaz, Diane Milne, Lesley Jardine et al. · Biochemical Journal · 2001 · 69 citations · Full text

Serine 20, Molecular Regulation, Molecular Biology +19

Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover

Nicolas Dumaz, Diane Milne, Lesley Jardine et al. · Biochemical Journal · 2001 · 44 citations

Serine 20, Molecular Regulation, Molecular Biology +19

Murine p53 is phosphorylated within the PAb421 epitope by protein kinase C in vitro, but not in vivo, even after stimulation with the phorbol ester o-tetradecanoylphorbol 13-acetate.

Diane Milne, Linda McKendrick, Lesley Jardine et al. · PubMed · 1996 · 38 citations