Andrei L. Okorokov

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.

Robert te Poele, Andrei L. Okorokov, Lesley Jardine et al. · PubMed · 2002 · 646 citations

Lifespan Extension, Tumor Biology, Genome Instability +15

Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A

Elena Bochkareva, Lilia Kaustov, Ayeda Ayed et al. · Proceedings of the National Academy of Sciences · 2005 · 278 citations · Full text

The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity

Andrei L. Okorokov, Michael B. Sherman, Célia Plisson‐Chastang et al. · The EMBO Journal · 2006 · 126 citations · Full text

Functional Plasticity, Lineage Plasticity, Medicine +6

Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity

Abdella M. Habib, Andrei L. Okorokov, Matthew N. Hill et al. · British Journal of Anaesthesia · 2019 · 122 citations · Full text

Pain Therapy, Pain Medicine, Neuropathic Pain +18

Induced N- and C-terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53

Andrei L. Okorokov, Frédérique Ponchel, Jo Milner · The EMBO Journal · 1997 · 65 citations · Full text

Core Fragment, Genome Instability, Molecular Biology +5