Molecular and spatial signatures of mouse brain aging at single-cell resolution

William E. Allen, Timothy R. Blosser, Zuri A. Sullivan, +2

Cell

AgingSpatial SignaturesSingle-cell ResolutionBiogerontologySpatial Omics +19

γδ T cells regulate the intestinal response to nutrient sensing

Zuri A. Sullivan, William Khoury-Hanold, Jaechul Lim, +14

Science

NutritionImmunologyGastroenterologyImmune RegulationDigestive Tract +18

Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis

Amanda J. Martinot, Mary F. Farrow, Lu Bai, +11

PLoS Pathogens

Metabolic DisorderLipoprotein LprgPathologyMetabolic SyndromeGrowth Rate +14

Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection

Emily Wong, Ngomu Akeem Akilimali, Pamla Govender, +9

PLoS ONE

Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV

Zuri A. Sullivan, Emily Wong, Thumbi Ndung’u, +2

EBioMedicine

TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis

Emily Wong, Marielle C. Gold, Erin W. Meermeier, +25

Communications Biology

A hypothalamic circuit underlying the dynamic control of social homeostasis

Ding Liu, Mohammed Mostafizur Rahman, Autumn Johnson, +15

Nature

Perturb-Multimodal: A platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue

Reuben A. Saunders, William E. Allen, Xingjie Pan, +8

Cell

Bettering BCG: a tough task for a TB vaccine?

William R. Bishai, Zuri A. Sullivan, Barry R. Bloom, +1

Nature Medicine

VaccinationPulmonary TuberculosisTuberculosis PreventionImmunologyTuberculosis +3

Intestinal mast cell–derived leukotrienes mediate the anaphylactic response to ingested antigens

Nathaniel D. Bachtel, Jaime L. Cullen, Min Liu, +10

Science