Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections

Judith N. Mandl, Ashley P. Barry, Thomas H. Vanderford, +7

Nature Medicine

Divergent Tlr7Human RetrovirusPathogenesisViral PathogenesisImmunology +9

T Cell-Positive Selection Uses Self-Ligand Binding Strength to Optimize Repertoire Recognition of Foreign Antigens

Judith N. Mandl, João P. Monteiro, Nienke Vrisekoop, +1

Immunity

Autoimmune DiseaseAdaptive Immune SystemRepertoire RecognitionT-regulatory CellImmunology +10

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

Qian Zhang, Christopher G. Dove, Jyh Liang Hor, +15

The Journal of Experimental Medicine

Inherited Combined ImmunodeficiencySkin Antiviral ImmunityMedicineViral PathogenesisImmunology +12

Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naïve CD4 ⁺ and CD8 ⁺ T cells

Judith N. Mandl, Rachel Liou, Frederick Klauschen, +5

Proceedings of the National Academy of Sciences

Pathology in euthermic bats with white nose syndrome suggests a natural manifestation of immune reconstitution inflammatory syndrome

Carol U. Meteyer, Daniel L. Barber, Judith N. Mandl

Virulence

InflammationAutoimmune DiseaseAllergyWhite Nose SyndromeZoonotic Disease +13

Understanding the transmission dynamics of respiratory syncytial virus using multiple time series and nested models

Lisa J. White, Judith N. Mandl, M. Gabriela M. Gomes, +10

Mathematical Biosciences

VaccinationMultiple Time SeriesTransmission DynamicsViral EvolutionInfectious Disease Modelling +13

Revisiting Thymic Positive Selection and the Mature T Cell Repertoire for Antigen

Nienke Vrisekoop, João P. Monteiro, Judith N. Mandl, +1

Immunity

Autoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunologyThymic Positive Selection +8

IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity

Carla Lippens, Fernanda V. Durães, Juan Dubrot, +7

Journal of Autoimmunity

Clinical ImmunologyT-regulatory CellImmunologyImmune RegulationImmunologic Mechanism +14

CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection

Kyoko E. Yuki, Hadir Marei, Evgenij Fiškin, +8

Nature Microbiology

Bacterial InfectionCell RegulationMolecular RegulationNatural SciencesMolecular Biology +8

Random Migration and Signal Integration Promote Rapid and Robust T Cell Recruitment

Johannes Textor, Sarah E. Henrickson, Judith N. Mandl, +4

PLoS Computational Biology

Random MigrationT-regulatory CellImmunologyRare T CellsImmunotherapy +15