Richard Söll

Deep learning enables rapid identification of potent DDR1 kinase inhibitors

Alex Zhavoronkov, Yan A. Ivanenkov, Alex Aliper et al. · Nature Biotechnology · 2019 · 1.4K citations

Drug Target, Engineering, De Novo Drug Design +10

Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera

Gerlinde Wernig, Michael G. Kharas, Rachel Okabe et al. · Cancer Cell · 2008 · 380 citations · Full text

Medicine, Jak2v617f-induced Polycythemia Vera, Murine Model +8

Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

Sara M. Weis, Satoshi Shintani, Alberto Weber et al. · Journal of Clinical Investigation · 2004 · 321 citations · Full text

Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

Sara M. Weis, Satoshi Shintani, Alberto Weber et al. · Journal of Clinical Investigation · 2004 · 295 citations · Full text

TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations

Animesh Pardanani, John Hood, Terra L. Lasho et al. · Leukemia · 2007 · 281 citations

Hematological Malignancy, Receptor Tyrosine Kinase, Myeloproliferative Disorder-associated Jak2v617f +8