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TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations

Hematological MalignancyReceptor Tyrosine KinaseMyeloproliferative Disorder-associated Jak2v617fHematologyMplw515l/k MutationsSystems BiologyMedicineCell BiologyCell SignalingJak-stat Signaling PathwayMyeloid Neoplasia